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A schematic representation of an SPR DNA origami biosensor setup. A gold film has a light source directed at it through a glass prism. This generates the surface plasmons in the form of oscillating plasmon waves due to the free plasmons in the metal. The presence of DNA origami with the analytes that are immobilised onto the gold surface at precise and controlled positions shifts the angle of the reflected light, leading to the most optimal SPR signal to be monitored with a detector. Created with BioRender.com.

Journal: Biosensors

Article Title: DNA Origami and Their Application in Biosensors

doi: 10.3390/bios16050247

Figure Lengend Snippet: A schematic representation of an SPR DNA origami biosensor setup. A gold film has a light source directed at it through a glass prism. This generates the surface plasmons in the form of oscillating plasmon waves due to the free plasmons in the metal. The presence of DNA origami with the analytes that are immobilised onto the gold surface at precise and controlled positions shifts the angle of the reflected light, leading to the most optimal SPR signal to be monitored with a detector. Created with BioRender.com.

Article Snippet: 1990 , The first commercial SPR biosensor , This was created by a company known as Pharmacia Biacore, which determined molecules’ characteristics through affinity and kinetics [ ]. .

Techniques: